Gene Synthesis Market Size, Growth, Trends and 2026 Forecast Report

Gene synthesis is a simple, convenient, and alternative method used for traditional cloning of animals and other projects. The technique is also used to synthesize naturally occurring gene sequences, gene libraries, codon-optimized genes, complex gene sequences, large gene sequences, or any other gene sequences. Gene synthesis can be used for research, disease treatment, and biotechnological research. Molecular applications of gene synthesis include disease diagnosis, clinical prognosis, protein engineering, metabolic engineering, and synthesis of yeast genome.

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Major advancements in the synthesis of certain genes that contribute to diseases, increase in the demand for mycobacterial identification in laboratories, rise in genetic characterization of diseases, and surge in the demand for human genome research are likely to boost the demand for gene synthesis in the near future. Several factors such as streamlined simplicity and flexibility in codon optimization, protein expression, and mutagenesis services make gene synthesis a highly adoptable technique for research and various diagnostic testing applications. The gene synthesis technology employs transcription activator-like effectors or any customized DNA constructs to do research on cancer biology, neuroscience, virology, and vaccine design. However, development of new pharmacological and gene therapy approaches are paving the way for early diagnosis and treatment of diseases, which can give a competition to the gene synthesis technology in the near future.

High prevalence of diseases such as neural disorders, cancer, cardiovascular and genetic diseases; rising awareness among patients, and increasing research and development activities are expected to drive the global gene synthesis market in the next few years. Furthermore, advent of gene therapy in agriculture, rise in government funding, and increase in the number of genomics projects are driving the global gene synthesis market. CRISPR/Cas9 system is widely used for genome location of bacteria during research in the pharmaceutical industry.

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For instance, Dharmacon, a Horizon Discovery Group company, has introduced CRISPR-Cas9 systems which can be used directly into eukaryotic systems. In December 2017, CRISPR therapeutics were approved in terms of the regulatory standpoint such as clinical trial test, duration of process, etc. CRISPR Therapeutics AG has submitted CTX001, which is the first application for a clinical trial testing its own company’s gene therapy technique in a blood disorder known as beta thalassemia. Growing number of pharmaceutical and biotechnology companies, increasing number of patients with neural diseases, and rising awareness about improved therapeutics are estimated to fuel the global gene synthesis market during the forecast period. However, factors such as high cost of sequencing methodologies and their time consuming nature are likely to hamper the global gene synthesis market from 2018 to 2026.

The global gene synthesis market can be segmented based on sequence length type, application type, end-user, and region. In terms of sequence length type, the market has been segmented into below 500 bp, 501–3000 bp, 3001–5000 bp, and above 5000 bp. The sequence length type segment products are made by the company’s on registering with an order for the sequence needed for research. The product shows variations in production time ability depending on the complexity of DNA sequence i.e. typical production time of sequencing are approximately more than 90% of genes produced. The production time ability of sequencing methodology is likely to increase in large data analytics function and synthetic biology process practiced by biotech companies, hence the production liability factor is expected to grow the demand of different sequence length type genes in near future.

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In terms of application type, the gene synthesis market has been segmented into synthetic biology, neuroscience, cancer biology, genetic engineering, vaccine design, and others. Synthetic biology is a rapidly expanding segment owing to worldwide increase in funds for research and development and growing research on protein engineering. Resistance of bacteria and viruses to approved drugs available in the market is also a major factor likely to fuel the genetic engineering application segment in the near future. In terms of end-user, the market can be segregated into research & academics, contract research organizations (CROs), pharmaceutical and biotechnology companies, and others. In terms of region, the market can be segmented into North America, Europe, Asia Pacific, and Rest of World.

Geographically, North America dominates the global gene synthesis market, due to the increase in funding for research as well as the development of health care infrastructure. Rising incidence of cancer and early-stage diagnosis and treatment of other chronic diseases are driving the biotechnology sector. This, in turn, is expected to boost the gene synthesis market in North America during the forecast period. Europe is the second-largest market for gene synthesis, as government policies regarding the development of health care infrastructure in the region are favorable. Expansion of research and development units in countries of Europe is also a major factor expected to drive the gene synthesis market in Europe in the near future. The market in Asia Pacific is expected to expand at a high growth rate during the forecast period, due to increase in genetically modified bacteria, fungi, and viruses leading to rise in the number of R&D centers; increasing awareness among patients about gene analysis; and rising per capita expenditure on health care in the region. Additionally, the economic growth in India and China is supporting the health care infrastructure. Also, expansion of pharmaceutical companies and biotech labs is likely to drive the market in Asia Pacific during the forecast period.

Major players operating in the global gene synthesis market are GenScript, GeneArt (Thermofischer), Genewiz, Integrated DNA Technologies, Inc., OriGene, ATDBio Ltd., and Eurofins Genomics LLC.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

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rohit patil Joined: March 26th, 2018